Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Toll-like receptor 8 (Homo sapiens (Human)) | BDBM50056696 (CHEMBL2270741) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.96E+3 | n/a | n/a | n/a | n/a |
University of Kansas Curated by ChEMBL | Assay Description Agonist activity at human TLR8 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liquid... | J Med Chem 57: 7325-41 (2014) Article DOI: 10.1021/jm500701q BindingDB Entry DOI: 10.7270/Q2JS9S3S | |||||||||||
More data for this Ligand-Target Pair |