Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Toll-like receptor 8' and Ligand = 'BDBM50124350'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50124350 (CHEMBL3622839) Show SMILES Cl.CCCCCc1c(N)nc2ccccc2c1Cc1cccc(CN)c1 Show InChI InChI=1S/C22H27N3.ClH/c1-2-3-4-11-19-20(14-16-8-7-9-17(13-16)15-23)18-10-5-6-12-21(18)25-22(19)24;/h5-10,12-13H,2-4,11,14-15,23H2,1H3,(H2,24,25);1H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Agonist activity at human TLR8 transfected in HEK293 cells assessed as activation of NF-kB by reporter gene assay				J Med Chem 58: 7833-49 (2015) Article DOI: 10.1021/acs.jmedchem.5b01087 BindingDB Entry DOI: 10.7270/Q2CF9RZK
					More data for this Ligand-Target Pair