Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Toll-like receptor 9' and Ligand = 'BDBM235730'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 9 (Homo sapiens (Human))	BDBM235730 (US10117875, Example 73 | US9359361, 73) Show SMILES CN1CCN(CCNc2nc(nc3n(CCN4CCN(C)CC4)c(=O)c(nc23)-c2ccccc2)-c2ccccc2)CC1 Show InChI InChI=1S/C32H41N9O/c1-37-15-19-39(20-16-37)14-13-33-30-28-31(36-29(35-30)26-11-7-4-8-12-26)41(24-23-40-21-17-38(2)18-22-40)32(42)27(34-28)25-9-5-3-6-10-25/h3-12H,13-24H2,1-2H3,(H,33,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	124	n/a	n/a	n/a	n/a	n/a	n/a
JANUS BIOTHERAPEUTICS, INC. US Patent					Assay Description HEK-Blue-hTLR9 cells were obtained from InvivoGen Inc. and used to determine test compound antagonism of human TLR9 (hTLR9) driven responses. HEK-Blu...				US Patent US10117875 (2018) BindingDB Entry DOI: 10.7270/Q2MK6FXT
					More data for this Ligand-Target Pair
Toll-like receptor 9 (Homo sapiens (Human))	BDBM235730 (US10117875, Example 73 | US9359361, 73) Show SMILES CN1CCN(CCNc2nc(nc3n(CCN4CCN(C)CC4)c(=O)c(nc23)-c2ccccc2)-c2ccccc2)CC1 Show InChI InChI=1S/C32H41N9O/c1-37-15-19-39(20-16-37)14-13-33-30-28-31(36-29(35-30)26-11-7-4-8-12-26)41(24-23-40-21-17-38(2)18-22-40)32(42)27(34-28)25-9-5-3-6-10-25/h3-12H,13-24H2,1-2H3,(H,33,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	124	n/a	n/a	n/a	n/a	n/a	37
JANUS BIOTHERAPEUTICS, INC. US Patent					Assay Description Day 1: A cell suspension of HEK-Blue™-hTLR9 cells at ~450,000 cells per ml in test medium which contained 5% (v/v) heat inactivated FBS was pre...				US Patent US9359361 (2016) BindingDB Entry DOI: 10.7270/Q2GH9GT3
					More data for this Ligand-Target Pair