Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transcription activator BRG1' and Ligand = 'BDBM50469324'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50469324 (CHEMBL4286345) Show SMILES Nc1cnc(Cl)cc1NC(=O)Nc1cc(ns1)C(F)F Show InChI InChI=1S/C10H8ClF2N5OS/c11-7-1-5(4(14)3-15-7)16-10(19)17-8-2-6(9(12)13)18-20-8/h1-3,9H,14H2,(H2,15,16,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant His6-tagged BRG1 ATPase-SnAC (658 to 1361 residues) (unknown origin) expressed in insect sf9 cells preincubated for 5 mins ...				J Med Chem 61: 10155-10172 (2018) Article DOI: 10.1021/acs.jmedchem.8b01318 BindingDB Entry DOI: 10.7270/Q2TH8QDB
					More data for this Ligand-Target Pair