Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human)) | BDBM50504160 (CHEMBL3133807 | US11773085, Compound B25) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | PDB PubMed | n/a | n/a | n/a | 5.53E+3 | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Reverse ITC (compound as receptor). Domain start/stop: R1398-D1524 | Sci Adv 2: (2016) BindingDB Entry DOI: 10.7270/Q24J0JPZ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human)) | BDBM50504160 (CHEMBL3133807 | US11773085, Compound B25) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | PDB PubMed | n/a | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Reverse ITC (compound as receptor). Domain start/stop: D1522-D1656 | Sci Adv 2: (2016) BindingDB Entry DOI: 10.7270/Q24J0JPZ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human)) | BDBM50504160 (CHEMBL3133807 | US11773085, Compound B25) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to TAF1 BD 1 (unknown origin) assessed as dissociation constant | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01999 BindingDB Entry DOI: 10.7270/Q2J96B94 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human)) | BDBM50504160 (CHEMBL3133807 | US11773085, Compound B25) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to TAF1 BD 2 (unknown origin) assessed as dissociation constant | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01999 BindingDB Entry DOI: 10.7270/Q2J96B94 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human)) | BDBM50504160 (CHEMBL3133807 | US11773085, Compound B25) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 147 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to human TAF1 tandem bromodomain (1373 to 1499 residues) transfected in Escherichia coli BL21 (DE3) assessed as dissociation constan... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01999 BindingDB Entry DOI: 10.7270/Q2J96B94 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |