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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transcription initiation factor TFIID subunit 1 [1504-1635]' and Ligand = 'BDBM346506'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transcription initiation factor TFIID subunit 1 [1504-1635]


(Homo sapiens (Human))		BDBM346506
PNG
((2-cyanophenyl)methyl 4-(3-hydroxy-3-methyl-but-1-...)
Show SMILES Cc1[nH]c2c(c1C(=O)OCc1ccccc1C#N)c(cn(C)c2=O)C#CC(C)(C)O
Show InChI InChI=1S/C23H21N3O4/c1-14-18(22(28)30-13-17-8-6-5-7-15(17)11-24)19-16(9-10-23(2,3)29)12-26(4)21(27)20(19)25-14/h5-8,12,25,29H,13H2,1-4H3
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 29.4n/an/an/an/an/an/a



GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent


Assay Description
His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...

US Patent US10202378 (2019)


BindingDB Entry DOI: 10.7270/Q22B9149
More data for this
Ligand-Target Pair