Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transcription initiation factor TFIID subunit 1 [1504-1635]' and Ligand = 'BDBM346545'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346545 (2-methylbutyl 4-(3-hydroxy-3-methyl-but-1-ynyl)-2,...) Show SMILES CCC(C)COC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(C)O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19.4	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair