Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential M8 protein' and Ligand = 'BDBM248356'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM248356 (US9434711, 213) Show SMILES OCc1c(sc2ccccc12)N(Cc1ccc(F)c(F)c1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C22H17F2NO3S2/c23-19-11-10-15(12-20(19)24)13-25(30(27,28)16-6-2-1-3-7-16)22-18(14-26)17-8-4-5-9-21(17)29-22/h1-12,26H,13-14H2	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	37
Janssen Pharmaceutica, N.V. US Patent					Assay Description The functional activity of compounds of the formula (I) was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensi...				US Patent US9434711 (2016) BindingDB Entry DOI: 10.7270/Q2H41QB6
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