Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential M8 protein' and Ligand = 'BDBM248365'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM248365 (US9434711, 222) Show SMILES CC(O)c1c(sc2ccccc12)N(Cc1ccc(F)c(F)c1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C23H19F2NO3S2/c1-15(27)22-18-9-5-6-10-21(18)30-23(22)26(14-16-11-12-19(24)20(25)13-16)31(28,29)17-7-3-2-4-8-17/h2-13,15,27H,14H2,1H3	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	37
Janssen Pharmaceutica, N.V. US Patent					Assay Description The functional activity of compounds of the formula (I) was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensi...				US Patent US9434711 (2016) BindingDB Entry DOI: 10.7270/Q2H41QB6
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