Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential M8 protein' and Ligand = 'BDBM248549'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM248549 (US9434711, 453) Show SMILES OC(=O)c1ccc(cc1)S(=O)(=O)N(CCOC1CCCCC1)c1sc2ccccc2c1Br Show InChI InChI=1S/C23H24BrNO5S2/c24-21-19-8-4-5-9-20(19)31-22(21)25(14-15-30-17-6-2-1-3-7-17)32(28,29)18-12-10-16(11-13-18)23(26)27/h4-5,8-13,17H,1-3,6-7,14-15H2,(H,26,27)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	37
Janssen Pharmaceutica, N.V. US Patent					Assay Description The functional activity of compounds of the formula (I) was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensi...				US Patent US9434711 (2016) BindingDB Entry DOI: 10.7270/Q2H41QB6
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