Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential M8 protein' and Ligand = 'BDBM248564'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM248564 (US9434711, 475) Show SMILES Fc1ccc(CN(c2sc3ccccc3c2Br)S(=O)(=O)c2ccc(cc2)-c2nnn[nH]2)cc1C(F)(F)F Show InChI InChI=1S/C23H14BrF4N5O2S2/c24-20-16-3-1-2-4-19(16)36-22(20)33(12-13-5-10-18(25)17(11-13)23(26,27)28)37(34,35)15-8-6-14(7-9-15)21-29-31-32-30-21/h1-11H,12H2,(H,29,30,31,32)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	37
Janssen Pharmaceutica, N.V. US Patent					Assay Description The functional activity of compounds of the formula (I) was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensi...				US Patent US9434711 (2016) BindingDB Entry DOI: 10.7270/Q2H41QB6
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