Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential M8 protein' and Ligand = 'BDBM248577'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM248577 (US9434711, 490) Show SMILES Cc1c(sc2ccccc12)N(Cc1ccc(OC(F)F)cc1)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C24H19F2NO5S2/c1-15-20-4-2-3-5-21(20)33-22(15)27(14-16-6-10-18(11-7-16)32-24(25)26)34(30,31)19-12-8-17(9-13-19)23(28)29/h2-13,24H,14H2,1H3,(H,28,29)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	37
Janssen Pharmaceutica, N.V. US Patent					Assay Description The functional activity of compounds of the formula (I) was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensi...				US Patent US9434711 (2016) BindingDB Entry DOI: 10.7270/Q2H41QB6
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