Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential M8 protein' and Ligand = 'BDBM248736'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential M8 protein (Canis lupus familiaris (Dog))	BDBM248736 (US9434711, 687) Show SMILES FC(F)(F)CCCCN(c1cc2ccccc2s1)S(=O)(=O)c1ccc(cc1)-c1nsc(=O)[nH]1 Show InChI InChI=1S/C21H18F3N3O3S3/c22-21(23,24)11-3-4-12-27(18-13-15-5-1-2-6-17(15)31-18)33(29,30)16-9-7-14(8-10-16)19-25-20(28)32-26-19/h1-2,5-10,13H,3-4,11-12H2,(H,25,26,28)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	56.9	n/a	n/a	n/a	n/a	n/a	37
Janssen Pharmaceutica, N.V. US Patent					Assay Description The functional activity of compounds of the formula (I) was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensi...				US Patent US9434711 (2016) BindingDB Entry DOI: 10.7270/Q2H41QB6
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