Compile Data Set for Download or QSAR

Found 9 hits Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily M member 8' and Ligand = 'BDBM435154'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM435154 (US10584134, Example 2-1 | US10584134, Example 2-15...) Show SMILES COc1cnc(nc1NC(C)C)-c1ccccn1 Show InChI InChI=1S/C13H16N4O/c1-9(2)16-13-11(18-3)8-15-12(17-13)10-6-4-5-7-14-10/h4-9H,1-3H3,(H,15,16,17)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
SYMRISE AG; BASF SE US Patent					Assay Description A test comparable with that previously described in the literature by Behrendt H. J. et al., Br. J. Pharmacol. 141, 2004, 737-745, is carried out. Th...				US Patent US10584134 (2020) BindingDB Entry DOI: 10.7270/Q2FJ2K56
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM435154 (US10584134, Example 2-1 | US10584134, Example 2-15...) Show SMILES COc1cnc(nc1NC(C)C)-c1ccccn1 Show InChI InChI=1S/C13H16N4O/c1-9(2)16-13-11(18-3)8-15-12(17-13)10-6-4-5-7-14-10/h4-9H,1-3H3,(H,15,16,17)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	800	n/a	n/a	n/a	n/a
SYMRISE AG; BASF SE US Patent					Assay Description A test comparable with that previously described in the literature by Behrendt H. J. et al., Br. J. Pharmacol. 141, 2004, 737-745, is carried out. Th...				US Patent US10584134 (2020) BindingDB Entry DOI: 10.7270/Q2FJ2K56
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM435154 (US10584134, Example 2-1 | US10584134, Example 2-15...) Show SMILES COc1cnc(nc1NC(C)C)-c1ccccn1 Show InChI InChI=1S/C13H16N4O/c1-9(2)16-13-11(18-3)8-15-12(17-13)10-6-4-5-7-14-10/h4-9H,1-3H3,(H,15,16,17)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a
SYMRISE AG; BASF SE US Patent					Assay Description A test comparable with that previously described in the literature by Behrendt H. J. et al., Br. J. Pharmacol. 141, 2004, 737-745, is carried out. Th...				US Patent US10584134 (2020) BindingDB Entry DOI: 10.7270/Q2FJ2K56
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM435154 (US10584134, Example 2-1 | US10584134, Example 2-15...) Show SMILES COc1cnc(nc1NC(C)C)-c1ccccn1 Show InChI InChI=1S/C13H16N4O/c1-9(2)16-13-11(18-3)8-15-12(17-13)10-6-4-5-7-14-10/h4-9H,1-3H3,(H,15,16,17)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
SYMRISE AG; BASF SE US Patent					Assay Description A test comparable with that previously described in the literature by Behrendt H. J. et al., Br. J. Pharmacol. 141, 2004, 737-745, is carried out. Th...				US Patent US10584134 (2020) BindingDB Entry DOI: 10.7270/Q2FJ2K56
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM435154 (US10584134, Example 2-1 | US10584134, Example 2-15...) Show SMILES COc1cnc(nc1NC(C)C)-c1ccccn1 Show InChI InChI=1S/C13H16N4O/c1-9(2)16-13-11(18-3)8-15-12(17-13)10-6-4-5-7-14-10/h4-9H,1-3H3,(H,15,16,17)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	700	n/a	n/a	n/a	n/a
SYMRISE AG; BASF SE US Patent					Assay Description A test comparable with that previously described in the literature by Behrendt H. J. et al., Br. J. Pharmacol. 141, 2004, 737-745, is carried out. Th...				US Patent US10584134 (2020) BindingDB Entry DOI: 10.7270/Q2FJ2K56
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM435154 (US10584134, Example 2-1 | US10584134, Example 2-15...) Show SMILES COc1cnc(nc1NC(C)C)-c1ccccn1 Show InChI InChI=1S/C13H16N4O/c1-9(2)16-13-11(18-3)8-15-12(17-13)10-6-4-5-7-14-10/h4-9H,1-3H3,(H,15,16,17)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
SYMRISE AG; BASF SE US Patent					Assay Description A test comparable with that previously described in the literature by Behrendt H. J. et al., Br. J. Pharmacol. 141, 2004, 737-745, is carried out. Th...				US Patent US10584134 (2020) BindingDB Entry DOI: 10.7270/Q2FJ2K56
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM435154 (US10584134, Example 2-1 | US10584134, Example 2-15...) Show SMILES COc1cnc(nc1NC(C)C)-c1ccccn1 Show InChI InChI=1S/C13H16N4O/c1-9(2)16-13-11(18-3)8-15-12(17-13)10-6-4-5-7-14-10/h4-9H,1-3H3,(H,15,16,17)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	900	n/a	n/a	n/a	n/a
SYMRISE AG; BASF SE US Patent					Assay Description A test comparable with that previously described in the literature by Behrendt H. J. et al., Br. J. Pharmacol. 141, 2004, 737-745, is carried out. Th...				US Patent US10584134 (2020) BindingDB Entry DOI: 10.7270/Q2FJ2K56
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM435154 (US10584134, Example 2-1 | US10584134, Example 2-15...) Show SMILES COc1cnc(nc1NC(C)C)-c1ccccn1 Show InChI InChI=1S/C13H16N4O/c1-9(2)16-13-11(18-3)8-15-12(17-13)10-6-4-5-7-14-10/h4-9H,1-3H3,(H,15,16,17)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
SYMRISE AG; BASF SE US Patent					Assay Description A test comparable with that previously described in the literature by Behrendt H. J. et al., Br. J. Pharmacol. 141, 2004, 737-745, is carried out. Th...				US Patent US10584134 (2020) BindingDB Entry DOI: 10.7270/Q2FJ2K56
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM435154 (US10584134, Example 2-1 | US10584134, Example 2-15...) Show SMILES COc1cnc(nc1NC(C)C)-c1ccccn1 Show InChI InChI=1S/C13H16N4O/c1-9(2)16-13-11(18-3)8-15-12(17-13)10-6-4-5-7-14-10/h4-9H,1-3H3,(H,15,16,17)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a
SYMRISE AG; BASF SE US Patent					Assay Description A test comparable with that previously described in the literature by Behrendt H. J. et al., Br. J. Pharmacol. 141, 2004, 737-745, is carried out. Th...				US Patent US10584134 (2020) BindingDB Entry DOI: 10.7270/Q2FJ2K56
					More data for this Ligand-Target Pair