Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transient receptor potential cation channel subfamily M member 8 (Mus musculus) | BDBM50329105 (19(S)-Heyneanine | CHEMBL463317 | voacristine) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.70E+4 | n/a | n/a | n/a | n/a |
University of Shizuoka Curated by ChEMBL | Assay Description Agonist activity at mouse TRPM8 expressed in T-REx HEK cells assessed as increase in intracellular Ca2+ accumulation by Fluo-4 AM dye based fluoresce... | J. Nat. Prod. 77: 1831-8 (2014) Article DOI: 10.1021/np500235b BindingDB Entry DOI: 10.7270/Q27S7QDF | |||||||||||
More data for this Ligand-Target Pair |