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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily M member 8' and Ligand = 'BDBM50442415'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily M member 8


(Homo sapiens (Human))		BDBM50442415
PNG
(CHEMBL2440148)
Show SMILES Fc1cccc2C(=O)CC3(CCN(CC3)C(=O)Nc3ccc(OC(F)(F)F)cc3)Oc12
Show InChI InChI=1S/C21H18F4N2O4/c22-16-3-1-2-15-17(28)12-20(31-18(15)16)8-10-27(11-9-20)19(29)26-13-4-6-14(7-5-13)30-21(23,24)25/h1-7H,8-12H2,(H,26,29)
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Similars
Article
PubMed
n/an/a 182n/an/an/an/an/an/a



Glenmark Pharmaceuticals Ltd.

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced 45Ca2+ uptake incubated for 10 mins prior to icili...

Bioorg Med Chem 21: 6542-53 (2013)


Article DOI: 10.1016/j.bmc.2013.08.031
BindingDB Entry DOI: 10.7270/Q2TH8P5S
More data for this
Ligand-Target Pair