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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily M member 8' and Ligand = 'BDBM50442430'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily M member 8


(Homo sapiens (Human))		BDBM50442430
PNG
(CHEMBL2443081)
Show SMILES FC(F)(F)c1ccc(NC(=O)N2CCC3(CC2)CCc2ccccc2O3)cc1
Show InChI InChI=1S/C21H21F3N2O2/c22-21(23,24)16-5-7-17(8-6-16)25-19(27)26-13-11-20(12-14-26)10-9-15-3-1-2-4-18(15)28-20/h1-8H,9-14H2,(H,25,27)
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PC cid
PC sid
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Similars
Article
PubMed
n/an/a 281n/an/an/an/an/an/a



Glenmark Pharmaceuticals Ltd.

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced 45Ca2+ uptake incubated for 10 mins prior to icili...

Bioorg Med Chem 21: 6542-53 (2013)


Article DOI: 10.1016/j.bmc.2013.08.031
BindingDB Entry DOI: 10.7270/Q2TH8P5S
More data for this
Ligand-Target Pair