Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 1' and Ligand = 'BDBM125057'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM125057 (US8765733, 5) Show SMILES CC1CCN(CC1)c1nc(ccc1CNC(=O)Nc1ccc(CNS(C)(=O)=O)cc1)C(F)(F)F Show InChI InChI=1S/C22H28F3N5O3S/c1-15-9-11-30(12-10-15)20-17(5-8-19(29-20)22(23,24)25)14-26-21(31)28-18-6-3-16(4-7-18)13-27-34(2,32)33/h3-8,15,27H,9-14H2,1-2H3,(H2,26,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gruenenthal GmbH US Patent					Assay Description The FLIPR protocol consists of 2 substance additions. First the compounds to be tested (10 μM) are pipetted onto the cells and the Ca2+ influx i...				US Patent US8765733 (2014) BindingDB Entry DOI: 10.7270/Q2BZ64QQ
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