Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 1' and Ligand = 'BDBM125074'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM125074 (US8765733, 63) Show SMILES CC(C(=O)NCc1ccc(nc1N1CCC(C)CC1)C(F)(F)F)c1ccc(CN(C)S(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C25H32F4N4O3S/c1-16-9-11-33(12-10-16)23-19(7-8-22(31-23)25(27,28)29)14-30-24(34)17(2)18-5-6-20(21(26)13-18)15-32(3)37(4,35)36/h5-8,13,16-17H,9-12,14-15H2,1-4H3,(H,30,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gruenenthal GmbH US Patent					Assay Description The FLIPR protocol consists of 2 substance additions. First the compounds to be tested (10 μM) are pipetted onto the cells and the Ca2+ influx i...				US Patent US8765733 (2014) BindingDB Entry DOI: 10.7270/Q2BZ64QQ
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