Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 1' and Ligand = 'BDBM20340'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM20340 (1-isoquinolin-5-yl-3-{[4-(4-methylpiperidin-1-yl)p...) Show SMILES CC1CCN(CC1)c1ccc(CNC(=O)Nc2cccc3cnccc23)cc1 Show InChI InChI=1S/C23H26N4O/c1-17-10-13-27(14-11-17)20-7-5-18(6-8-20)15-25-23(28)26-22-4-2-3-19-16-24-12-9-21(19)22/h2-9,12,16-17H,10-11,13-15H2,1H3,(H2,25,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.30	n/a	n/a	7.4	22
Abbott Laboratories					Assay Description The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...				J Med Chem 50: 3651-60 (2007) Article DOI: 10.1021/jm070276i BindingDB Entry DOI: 10.7270/Q2SJ1HWH
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