BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 1' and Ligand = 'BDBM50241321'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50241321 (CHEMBL249778 \| N-(4-(5-(dimethylamino)-6-(4-(trifl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in CHO cells assessed inhibition of acid induced calcium influx				Bioorg Med Chem Lett 17: 6539-45 (2007) Article DOI: 10.1016/j.bmcl.2007.09.080 BindingDB Entry DOI: 10.7270/Q2FX7961
Amgen Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50241321 (CHEMBL249778 \| N-(4-(5-(dimethylamino)-6-(4-(trifl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in CHO cells assessed inhibition of capsaicin induced calcium influx				Bioorg Med Chem Lett 17: 6539-45 (2007) Article DOI: 10.1016/j.bmcl.2007.09.080 BindingDB Entry DOI: 10.7270/Q2FX7961
Amgen Inc. Curated by ChEMBL					More data for this Ligand-Target Pair