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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 1' and Ligand = 'BDBM50391041'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM50391041
PNG
(CHEMBL2088407)
Show SMILES Cn1nc(cc1C(=O)Nc1ccc2sc(CO)nc2c1)C(F)(F)F
Show InChI InChI=1S/C14H11F3N4O2S/c1-21-9(5-11(20-21)14(15,16)17)13(23)18-7-2-3-10-8(4-7)19-12(6-22)24-10/h2-5,22H,6H2,1H3,(H,18,23)
PDB
MMDB

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PC cid
PC sid
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Article
PubMed
n/an/a 157n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant TRPV1 receptor assessed as inhibition of capsaicin-induced calcium uptake by FLIPR assay


Bioorg Med Chem Lett 22: 6205-11 (2012)


Article DOI: 10.1016/j.bmcl.2012.08.018
BindingDB Entry DOI: 10.7270/Q29C6ZGB
More data for this
Ligand-Target Pair