BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 1' and Ligand = 'BDBM50454340'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM50454340
PNG
(CHEMBL4215204)
Show SMILES O=C(Nc1ccccc1)N1CCN(CC1)C(=O)c1cc(nc2ccccc12)-c1ccccc1
Show InChI InChI=1S/C27H24N4O2/c32-26(30-15-17-31(18-16-30)27(33)28-21-11-5-2-6-12-21)23-19-25(20-9-3-1-4-10-20)29-24-14-8-7-13-22(23)24/h1-14,19H,15-18H2,(H,28,33)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 136n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced intracellular calcium level preincubated for 2.5 mins followed by caps...

Bioorg Med Chem 26: 845-854 (2018)


Article DOI: 10.1016/j.bmc.2017.12.048
BindingDB Entry DOI: 10.7270/Q27S7RDV
More data for this
Ligand-Target Pair