Compile Data Set for Download or QSAR

Found 6 hits Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 1' and Ligand = 'BDBM60942'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM60942 (US9273043, AE) Show SMILES C[C@@H]1CN(CCN1c1ncc(cc1F)[C@H](O)CO)C(=O)Nc1nc2cc(F)c(F)cc2s1 |r| Show InChI InChI=1S/C20H20F3N5O3S/c1-10-8-27(2-3-28(10)18-14(23)4-11(7-24-18)16(30)9-29)20(31)26-19-25-15-5-12(21)13(22)6-17(15)32-19/h4-7,10,16,29-30H,2-3,8-9H2,1H3,(H,25,26,31)/t10-,16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40.8	n/a	n/a	n/a	n/a	7.2	37
Purdue Pharma L.P.; Shionogi & Co., Ltd. US Patent					Assay Description pH dependent Ca2+ responses in TRPV1/CHO cells cultured in a 96-well plate were determined (see, e.g., FIG. 2 of U.S. Patent Application Publication ...				US Patent US9273043 (2016) BindingDB Entry DOI: 10.7270/Q2D7998G
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM60942 (US9273043, AE) Show SMILES C[C@@H]1CN(CCN1c1ncc(cc1F)[C@H](O)CO)C(=O)Nc1nc2cc(F)c(F)cc2s1 |r| Show InChI InChI=1S/C20H20F3N5O3S/c1-10-8-27(2-3-28(10)18-14(23)4-11(7-24-18)16(30)9-29)20(31)26-19-25-15-5-12(21)13(22)6-17(15)32-19/h4-7,10,16,29-30H,2-3,8-9H2,1H3,(H,25,26,31)/t10-,16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40.8	n/a	n/a	n/a	n/a	7.2	37
Purdue Pharma L.P.; Shionogi & Co., Ltd. US Patent					Assay Description pH dependent Ca2+ responses in TRPV1/CHO cells cultured in a 96-well plate were determined (see, e.g., FIG. 2 of U.S. Patent Application Publication ...				US Patent US9273043 (2016) BindingDB Entry DOI: 10.7270/Q2D7998G
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM60942 (US9273043, AE) Show SMILES C[C@@H]1CN(CCN1c1ncc(cc1F)[C@H](O)CO)C(=O)Nc1nc2cc(F)c(F)cc2s1 |r| Show InChI InChI=1S/C20H20F3N5O3S/c1-10-8-27(2-3-28(10)18-14(23)4-11(7-24-18)16(30)9-29)20(31)26-19-25-15-5-12(21)13(22)6-17(15)32-19/h4-7,10,16,29-30H,2-3,8-9H2,1H3,(H,25,26,31)/t10-,16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	68	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma L.P.; Shionogi & Co., Ltd. US Patent					Assay Description One day prior to assay, TRPV1/CHO cells were seeded in 96-well clear-bottom black plates (20,000 cells/well) in growth media. On the day of the exper...				US Patent US9273043 (2016) BindingDB Entry DOI: 10.7270/Q2D7998G
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM60942 (US9273043, AE) Show SMILES C[C@@H]1CN(CCN1c1ncc(cc1F)[C@H](O)CO)C(=O)Nc1nc2cc(F)c(F)cc2s1 |r| Show InChI InChI=1S/C20H20F3N5O3S/c1-10-8-27(2-3-28(10)18-14(23)4-11(7-24-18)16(30)9-29)20(31)26-19-25-15-5-12(21)13(22)6-17(15)32-19/h4-7,10,16,29-30H,2-3,8-9H2,1H3,(H,25,26,31)/t10-,16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	68	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma L.P.; Shionogi & Co., Ltd. US Patent					Assay Description One day prior to assay, TRPV1/CHO cells were seeded in 96-well clear-bottom black plates (20,000 cells/well) in growth media. On the day of the exper...				US Patent US9273043 (2016) BindingDB Entry DOI: 10.7270/Q2D7998G
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM60942 (US9273043, AE) Show SMILES C[C@@H]1CN(CCN1c1ncc(cc1F)[C@H](O)CO)C(=O)Nc1nc2cc(F)c(F)cc2s1 |r| Show InChI InChI=1S/C20H20F3N5O3S/c1-10-8-27(2-3-28(10)18-14(23)4-11(7-24-18)16(30)9-29)20(31)26-19-25-15-5-12(21)13(22)6-17(15)32-19/h4-7,10,16,29-30H,2-3,8-9H2,1H3,(H,25,26,31)/t10-,16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	37
Purdue Pharma L.P.; Shionogi & Co., Ltd. US Patent					Assay Description Briefly, hTRPV1/CHO cells were cultured in growth media in a tissue culture dish at 37° C. in a CO2 incubator. On the day of the assay, culture m...				US Patent US9273043 (2016) BindingDB Entry DOI: 10.7270/Q2D7998G
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM60942 (US9273043, AE) Show SMILES C[C@@H]1CN(CCN1c1ncc(cc1F)[C@H](O)CO)C(=O)Nc1nc2cc(F)c(F)cc2s1 |r| Show InChI InChI=1S/C20H20F3N5O3S/c1-10-8-27(2-3-28(10)18-14(23)4-11(7-24-18)16(30)9-29)20(31)26-19-25-15-5-12(21)13(22)6-17(15)32-19/h4-7,10,16,29-30H,2-3,8-9H2,1H3,(H,25,26,31)/t10-,16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	37
Purdue Pharma L.P.; Shionogi & Co., Ltd. US Patent					Assay Description Briefly, hTRPV1/CHO cells were cultured in growth media in a tissue culture dish at 37° C. in a CO2 incubator. On the day of the assay, culture m...				US Patent US9273043 (2016) BindingDB Entry DOI: 10.7270/Q2D7998G
					More data for this Ligand-Target Pair