Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 4' and Ligand = 'BDBM230227'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM230227 (US9340500, I-071) Show SMILES Cc1c(cc(-c2ccccc2)n1CCCN1CCNC(=O)C1)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C26H27F3N4O2/c1-18-22(25(35)31-21-10-5-9-20(15-21)26(27,28)29)16-23(19-7-3-2-4-8-19)33(18)13-6-12-32-14-11-30-24(34)17-32/h2-5,7-10,15-16H,6,11-14,17H2,1H3,(H,30,34)(H,31,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	196	-39.8	n/a	n/a	n/a	n/a	n/a	n/a	37
SHIONOGI & CO., LTD. US Patent					Assay Description Test Example 3: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) Frozen cells ...				US Patent US9340500 (2016) BindingDB Entry DOI: 10.7270/Q2319TR3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM230227 (US9340500, I-071) Show SMILES Cc1c(cc(-c2ccccc2)n1CCCN1CCNC(=O)C1)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C26H27F3N4O2/c1-18-22(25(35)31-21-10-5-9-20(15-21)26(27,28)29)16-23(19-7-3-2-4-8-19)33(18)13-6-12-32-14-11-30-24(34)17-32/h2-5,7-10,15-16H,6,11-14,17H2,1H3,(H,30,34)(H,31,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	37
SHIONOGI & CO., LTD. US Patent					Assay Description Test Example 1: (1) The TRPV4 inhibitory activity was measured using CHO-K1 cells stably expressing human TRPV4 (hTRPV4/CHO cells). (2) In the day be...				US Patent US9340500 (2016) BindingDB Entry DOI: 10.7270/Q2319TR3
					More data for this Ligand-Target Pair