Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Transient receptor potential cation channel subfamily V member 4' and Ligand = 'BDBM50232791'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50232791 (CHEMBL4062863) Show SMILES C[C@H](NC(=O)c1c(CN2CCC(CC2)N2CCCCC2)c(nc2ccccc12)-c1cccc(Cl)c1)c1ccccc1 |r| Show InChI InChI=1S/C35H39ClN4O/c1-25(26-11-4-2-5-12-26)37-35(41)33-30-15-6-7-16-32(30)38-34(27-13-10-14-28(36)23-27)31(33)24-39-21-17-29(18-22-39)40-19-8-3-9-20-40/h2,4-7,10-16,23,25,29H,3,8-9,17-22,24H2,1H3,(H,37,41)/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV4 expressed in HEK293 cells assessed as inhibition of GSK634775A-induced calcium influx preincubated for 10 mins follo...				ACS Med Chem Lett 8: 549-554 (2017) Article DOI: 10.1021/acsmedchemlett.7b00094 BindingDB Entry DOI: 10.7270/Q2HD7XWW
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50232791 (CHEMBL4062863) Show SMILES C[C@H](NC(=O)c1c(CN2CCC(CC2)N2CCCCC2)c(nc2ccccc12)-c1cccc(Cl)c1)c1ccccc1 |r| Show InChI InChI=1S/C35H39ClN4O/c1-25(26-11-4-2-5-12-26)37-35(41)33-30-15-6-7-16-32(30)38-34(27-13-10-14-28(36)23-27)31(33)24-39-21-17-29(18-22-39)40-19-8-3-9-20-40/h2,4-7,10-16,23,25,29H,3,8-9,17-22,24H2,1H3,(H,37,41)/t25-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 expressed in HEK293 cells assessed as inhibition of GSK634775A-induced calcium influx preincubated for 10 mins fol...				ACS Med Chem Lett 8: 549-554 (2017) Article DOI: 10.1021/acsmedchemlett.7b00094 BindingDB Entry DOI: 10.7270/Q2HD7XWW
					More data for this Ligand-Target Pair