Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transmembrane prolyl 4-hydroxylase' and Ligand = 'BDBM105219'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human))	BDBM105219 (US8580778, 17) Show SMILES FC1(F)CCN(C1)c1cc(ncn1)-n1[nH]cc(-n2cc(nn2)C#N)c1=O Show InChI InChI=1S/C14H11F2N9O/c15-14(16)1-2-23(7-14)11-3-12(19-8-18-11)25-13(26)10(5-20-25)24-6-9(4-17)21-22-24/h3,5-6,8,20H,1-2,7H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Intellectual Property GmbH US Patent					Assay Description In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ...				US Patent US8580778 (2013) BindingDB Entry DOI: 10.7270/Q21C1VH5
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