Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transmembrane prolyl 4-hydroxylase' and Ligand = 'BDBM105224'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transmembrane prolyl 4-hydroxylase (Homo sapiens (Human))	BDBM105224 (US8580778, 29) Show SMILES O=c1c(c[nH]n1-c1cc(ncn1)N1CCCCO1)-n1cc(nn1)C#N Show InChI InChI=1S/C14H13N9O2/c15-6-10-8-21(20-19-10)11-7-18-23(14(11)24)13-5-12(16-9-17-13)22-3-1-2-4-25-22/h5,7-9,18H,1-4H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Intellectual Property GmbH US Patent					Assay Description In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ...				US Patent US8580778 (2013) BindingDB Entry DOI: 10.7270/Q21C1VH5
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