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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transmembrane protease serine 6' and Ligand = 'BDBM50236916'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transmembrane protease serine 6


(Homo sapiens (Human))		BDBM50236916
PNG
(CHEMBL4070960)
Show SMILES CC(C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)c1nc2ccccc2s1 |r|
Show InChI InChI=1S/C36H44N8O5S/c1-21(2)30(34(49)41-27(12-8-18-40-36(38)39)31(46)35-43-26-11-6-7-13-29(26)50-35)44-33(48)28(20-22-9-4-3-5-10-22)42-32(47)25(37)19-23-14-16-24(45)17-15-23/h3-7,9-11,13-17,21,25,27-28,30,45H,8,12,18-20,37H2,1-2H3,(H,41,49)(H,42,47)(H,44,48)(H4,38,39,40)/t25-,27-,28-,30-/m0/s1
KEGG

UniProtKB/SwissProt

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Similars
Article
PubMed
 9n/an/an/an/an/an/an/an/a



Universit£ de Sherbrooke

Curated by ChEMBL


Assay Description
Inhibition of recombinant human C-terminal V5-His-tagged matriptase-2 expressed in Drosophila S2 cells using Boc-Gln-Ala-ArgAMC as substrate measured...

Eur J Med Chem 129: 110-123 (2017)


Article DOI: 10.1016/j.ejmech.2017.02.006
BindingDB Entry DOI: 10.7270/Q2GB269P
More data for this
Ligand-Target Pair