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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transmembrane protease serine 6' and Ligand = 'BDBM50236920'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transmembrane protease serine 6


(Homo sapiens (Human))		BDBM50236920
PNG
(CHEMBL4084047)
Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CCc1ccccc1)C(c1ccccc1)c1ccccc1)C(=O)c1nc2ccccc2s1 |r|
Show InChI InChI=1S/C46H47N7O5S/c47-46(48)49-28-12-20-36(42(56)45-52-35-19-10-11-21-38(35)59-45)51-44(58)41(40(32-15-6-2-7-16-32)33-17-8-3-9-18-33)53-43(57)37(29-31-22-25-34(54)26-23-31)50-39(55)27-24-30-13-4-1-5-14-30/h1-11,13-19,21-23,25-26,36-37,40-41,54H,12,20,24,27-29H2,(H,50,55)(H,51,58)(H,53,57)(H4,47,48,49)/t36-,37-,41-/m0/s1
KEGG

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PC sid
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Similars
Article
PubMed
 340n/an/an/an/an/an/an/an/a



Universit£ de Sherbrooke

Curated by ChEMBL


Assay Description
Inhibition of recombinant human C-terminal V5-His-tagged matriptase-2 expressed in Drosophila S2 cells using Boc-Gln-Ala-ArgAMC as substrate measured...

Eur J Med Chem 129: 110-123 (2017)


Article DOI: 10.1016/j.ejmech.2017.02.006
BindingDB Entry DOI: 10.7270/Q2GB269P
More data for this
Ligand-Target Pair