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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Transmembrane protease serine 6' and Ligand = 'BDBM50394295'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transmembrane protease serine 6


(Homo sapiens (Human))		BDBM50394295
PNG
(CHEMBL2159392)
Show SMILES COc1ccc(CNC(=O)CCCNS(=O)(=O)c2cccc(c2)C(N)=N)cc1OC
Show InChI InChI=1S/C20H26N4O5S/c1-28-17-9-8-14(11-18(17)29-2)13-23-19(25)7-4-10-24-30(26,27)16-6-3-5-15(12-16)20(21)22/h3,5-6,8-9,11-12,24H,4,7,10,13H2,1-2H3,(H3,21,22)(H,23,25)
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...

Bioorg Med Chem 20: 6489-505 (2012)


Article DOI: 10.1016/j.bmc.2012.08.042
BindingDB Entry DOI: 10.7270/Q2SB46VD
More data for this
Ligand-Target Pair