Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transporter (Rattus norvegicus) | BDBM50010195 ((3S,5R)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Research Biochemicals International Curated by ChEMBL | Assay Description In vitro binding affinity towards Norepinephrine transporter rat cerebral cortical homogenates by [3H]nisoxetine displacement. | J Med Chem 39: 543-8 (1996) Article DOI: 10.1021/jm9505324 BindingDB Entry DOI: 10.7270/Q2KD1ZJ5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus) | BDBM50010195 ((3S,5R)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from norepinephrine transporter of rat cerebral cortex | Bioorg Med Chem Lett 15: 1131-3 (2005) Article DOI: 10.1016/j.bmcl.2004.12.014 BindingDB Entry DOI: 10.7270/Q2PK0GXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus) | BDBM50010195 ((3S,5R)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro binding affinity of compound for Norepinephrine (NE) transporter with [3H]- nisoxatine as radioligand in corpus striatum tissue from rat for... | Bioorg Med Chem Lett 7: 337-340 (1997) Article DOI: 10.1016/S0960-894X(97)00009-7 BindingDB Entry DOI: 10.7270/Q2T72HGQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus) | BDBM50010195 ((3S,5R)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | PubMed | 7.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Inhibition of [3H]NE uptake by rat frontal cortex Norepinephrine transporter | J Med Chem 38: 379-88 (1995) BindingDB Entry DOI: 10.7270/Q2D50NM0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus) | BDBM50010195 ((3S,5R)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Binding potency for Norepinephrine transporter using [3H]NE | J Med Chem 39: 4139-41 (1996) Article DOI: 10.1021/jm960515u BindingDB Entry DOI: 10.7270/Q2JD4XGP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus) | BDBM50010195 ((3S,5R)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Binding affinity at the Norepinephrine transporter in rat frontal cortex by inhibition of 0.5 nM [3H]nisoxetine binding | J Med Chem 38: 379-88 (1995) BindingDB Entry DOI: 10.7270/Q2D50NM0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus) | BDBM50010195 ((3S,5R)-methyl 3-(4-iodophenyl)-8-methyl-8-aza-bic...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Binding potency for Norepinephrine transporter using [3H]NE | J Med Chem 39: 4139-41 (1996) Article DOI: 10.1021/jm960515u BindingDB Entry DOI: 10.7270/Q2JD4XGP | |||||||||||
More data for this Ligand-Target Pair |