Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transporter (Rattus norvegicus) | BDBM82217 (CHEMBL284994 | CP-52003 | SERTRALINE | [4-(3,4-Dic...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of norepinephrine uptake in synaptosomal preparation fro rat hypothalamus, using [3H]norepinephrine | J Med Chem 27: 1508-15 (1984) BindingDB Entry DOI: 10.7270/Q2WS8TTB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus) | BDBM82217 (CHEMBL284994 | CP-52003 | SERTRALINE | [4-(3,4-Dic...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of dopamine uptake in synaptosomal preparation in rat corpus striatum, using [3H]dopamine | J Med Chem 27: 1508-15 (1984) BindingDB Entry DOI: 10.7270/Q2WS8TTB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM82217 (CHEMBL284994 | CP-52003 | SERTRALINE | [4-(3,4-Dic...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Sepracor Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]norepinephrine reuptake at NET in rat brain synaptosome by scintillation counting | Bioorg Med Chem 19: 663-76 (2011) Article DOI: 10.1016/j.bmc.2010.10.034 BindingDB Entry DOI: 10.7270/Q2639Q0M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus) | BDBM82217 (CHEMBL284994 | CP-52003 | SERTRALINE | [4-(3,4-Dic...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of norepinephrine uptake in synaptosomal preparation fro rat hypothalamus, using [3H]norepinephrine | J Med Chem 27: 1508-15 (1984) BindingDB Entry DOI: 10.7270/Q2WS8TTB | |||||||||||
More data for this Ligand-Target Pair |