Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tryptase beta-2/delta/gamma' and Ligand = 'BDBM50144559'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tryptase beta-2/delta/gamma (Homo sapiens (Human))	BDBM50144559 ((R)-1-[4-(4-Naphthalen-2-yl-butyryl)-piperazine-1-...) Show SMILES OC(=O)[C@@H]1[C@@H](CC2CCNCC2)C(=O)N1C(=O)N1CCN(CC1)C(=O)CCCc1ccc2ccccc2c1 Show InChI InChI=1S/C29H36N4O5/c34-25(7-3-4-20-8-9-22-5-1-2-6-23(22)18-20)31-14-16-32(17-15-31)29(38)33-26(28(36)37)24(27(33)35)19-21-10-12-30-13-11-21/h1-2,5-6,8-9,18,21,24,26,30H,3-4,7,10-17,19H2,(H,36,37)/t24-,26+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
The Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against human tryptase				Bioorg Med Chem Lett 14: 2233-9 (2004) Article DOI: 10.1016/j.bmcl.2004.02.012 BindingDB Entry DOI: 10.7270/Q2SB4697
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