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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tryptase beta-2' and Ligand = 'BDBM14317'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tryptase beta-2


(Homo sapiens (Human))		BDBM14317
PNG
(CRA28 | N-[(2S)-1-(5-{[4-(2,3-dihydro-1H-inden-2-y...)
Show SMILES Fc1ccc(cc1F)C(=O)N[C@@H](CCC1CCNC1)C(=O)c1noc(Cc2ccc(cc2)C(=O)NC2Cc3ccccc3C2)n1 |r|
Show InChI InChI=1S/C34H33F2N5O4/c35-27-11-10-25(18-28(27)36)34(44)39-29(12-7-21-13-14-37-19-21)31(42)32-40-30(45-41-32)15-20-5-8-22(9-6-20)33(43)38-26-16-23-3-1-2-4-24(23)17-26/h1-6,8-11,18,21,26,29,37H,7,12-17,19H2,(H,38,43)(H,39,44)/t21?,29-/m0/s1
PDB
MMDB

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Article
PubMed
 21n/an/an/an/an/an/an/an/a



Celera



Assay Description
Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...

Biochemistry 45: 5964-73 (2006)


Article DOI: 10.1021/bi060173m
BindingDB Entry DOI: 10.7270/Q2W09450
More data for this
Ligand-Target Pair