Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tryptase beta-2' and Ligand = 'BDBM50152197'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tryptase beta-2 (Homo sapiens (Human))	BDBM50152197 (2-[3-(5-Aminomethyl-2,4-dimethyl-benzylamino)-5-ch...) Show SMILES Cc1cc(C)c(CNc2nc(Cl)c(C)n(CC(=O)Nc3cccc(CN)c3)c2=O)cc1CN Show InChI InChI=1S/C24H29ClN6O2/c1-14-7-15(2)19(9-18(14)11-27)12-28-23-24(33)31(16(3)22(25)30-23)13-21(32)29-20-6-4-5-17(8-20)10-26/h4-9H,10-13,26-27H2,1-3H3,(H,28,30)(H,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	93	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against human Tryptase beta 2 expressed in yeast cells				Bioorg Med Chem Lett 14: 4819-23 (2004) Article DOI: 10.1016/j.bmcl.2004.07.051 BindingDB Entry DOI: 10.7270/Q2H994NZ
					More data for this Ligand-Target Pair