Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tryptase beta-2' and Ligand = 'BDBM50152205'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tryptase beta-2 (Homo sapiens (Human))	BDBM50152205 (2-[3-(3-Aminomethyl-benzylamino)-5-chloro-6-methyl...) Show SMILES Cc1c(Cl)nc(NCc2cccc(CN)c2)c(=O)n1CC(=O)Nc1cccc(CN)c1 Show InChI InChI=1S/C22H25ClN6O2/c1-14-20(23)28-21(26-12-17-6-2-4-15(8-17)10-24)22(31)29(14)13-19(30)27-18-7-3-5-16(9-18)11-25/h2-9H,10-13,24-25H2,1H3,(H,26,28)(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against human Tryptase beta 2 expressed in yeast cells				Bioorg Med Chem Lett 14: 4819-23 (2004) Article DOI: 10.1016/j.bmcl.2004.07.051 BindingDB Entry DOI: 10.7270/Q2H994NZ
					More data for this Ligand-Target Pair