Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tryptase beta-2' and Ligand = 'BDBM50152206'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tryptase beta-2 (Homo sapiens (Human))	BDBM50152206 (CHEMBL187587 | N-(3-Aminomethyl-phenyl)-2-{5-chlor...) Show SMILES Cc1c(Cl)nc(NCCc2cnc[nH]2)c(=O)n1CC(=O)Nc1cccc(CN)c1 Show InChI InChI=1S/C19H22ClN7O2/c1-12-17(20)26-18(23-6-5-15-9-22-11-24-15)19(29)27(12)10-16(28)25-14-4-2-3-13(7-14)8-21/h2-4,7,9,11H,5-6,8,10,21H2,1H3,(H,22,24)(H,23,26)(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	426	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against human Tryptase beta 2 expressed in yeast cells				Bioorg Med Chem Lett 14: 4819-23 (2004) Article DOI: 10.1016/j.bmcl.2004.07.051 BindingDB Entry DOI: 10.7270/Q2H994NZ
					More data for this Ligand-Target Pair