Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tryptase beta-2' and Ligand = 'BDBM50167527'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tryptase beta-2 (Homo sapiens (Human))	BDBM50167527 (CHEMBL189983 | [4-(3-Aminomethyl-phenyl)-piperidin...) Show SMILES NCc1cccc(c1)C1CCN(CC1)C(=O)c1c[nH]c2c(F)cccc12 Show InChI InChI=1S/C21H22FN3O/c22-19-6-2-5-17-18(13-24-20(17)19)21(26)25-9-7-15(8-10-25)16-4-1-3-14(11-16)12-23/h1-6,11,13,15,24H,7-10,12,23H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	368	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against tryptase				Bioorg Med Chem Lett 15: 2734-7 (2005) Article DOI: 10.1016/j.bmcl.2005.04.002 BindingDB Entry DOI: 10.7270/Q2V987K1
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