Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tryptophan 5-hydroxylase 1' and Ligand = 'BDBM50234201'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tryptophan 5-hydroxylase 1 (Homo sapiens (Human))	BDBM50234201 (CHEMBL4078797) Show SMILES CC(C)(C)c1cccc(c1)-c1cc(Cl)ccc1[C@@H](Oc1cc(nc(N)n1)N1CCC2(CN[C@@H](C2)C(O)=O)CC1)C(F)(F)F |r| Show InChI InChI=1S/C31H35ClF3N5O3/c1-29(2,3)19-6-4-5-18(13-19)22-14-20(32)7-8-21(22)26(31(33,34)35)43-25-15-24(38-28(36)39-25)40-11-9-30(10-12-40)16-23(27(41)42)37-17-30/h4-8,13-15,23,26,37H,9-12,16-17H2,1-3H3,(H,41,42)(H2,36,38,39)/t23-,26+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Karos Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of TPH1 (unknown origin)				Bioorg Med Chem Lett 27: 413-419 (2017) Article DOI: 10.1016/j.bmcl.2016.12.053 BindingDB Entry DOI: 10.7270/Q21V5H7S
					More data for this Ligand-Target Pair