Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tryptophan 5-hydroxylase 1' and Ligand = 'BDBM50234205'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tryptophan 5-hydroxylase 1 (Homo sapiens (Human))	BDBM50234205 (CHEMBL4088856) Show SMILES Nc1nc(O[C@H](c2ccc(cc2)-c2ccc3cnccc3c2)C(F)(F)F)cc(n1)N1CCC2(CN[C@@H](C2)C(O)=O)CC1 |r| Show InChI InChI=1S/C30H29F3N6O3/c31-30(32,33)26(19-3-1-18(2-4-19)20-5-6-22-16-35-10-7-21(22)13-20)42-25-14-24(37-28(34)38-25)39-11-8-29(9-12-39)15-23(27(40)41)36-17-29/h1-7,10,13-14,16,23,26,36H,8-9,11-12,15,17H2,(H,40,41)(H2,34,37,38)/t23-,26+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Karos Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of TPH1 (unknown origin)				Bioorg Med Chem Lett 27: 413-419 (2017) Article DOI: 10.1016/j.bmcl.2016.12.053 BindingDB Entry DOI: 10.7270/Q21V5H7S
					More data for this Ligand-Target Pair