Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tryptophan 5-hydroxylase 1' and Ligand = 'BDBM50234206'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tryptophan 5-hydroxylase 1 (Homo sapiens (Human))	BDBM50234206 (CHEMBL4060885) Show SMILES CSc1ccc2cc(ccc2n1)-c1ccc(cc1)[C@@H](Oc1cc(nc(N)n1)N1CCC2(CN[C@@H](C2)C(O)=O)CC1)C(F)(F)F |r| Show InChI InChI=1S/C31H31F3N6O3S/c1-44-26-9-7-21-14-20(6-8-22(21)37-26)18-2-4-19(5-3-18)27(31(32,33)34)43-25-15-24(38-29(35)39-25)40-12-10-30(11-13-40)16-23(28(41)42)36-17-30/h2-9,14-15,23,27,36H,10-13,16-17H2,1H3,(H,41,42)(H2,35,38,39)/t23-,27+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Karos Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of TPH1 (unknown origin)				Bioorg Med Chem Lett 27: 413-419 (2017) Article DOI: 10.1016/j.bmcl.2016.12.053 BindingDB Entry DOI: 10.7270/Q21V5H7S
					More data for this Ligand-Target Pair