Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tryptophan 5-hydroxylase 2 (Homo sapiens (Human)) | BDBM50233990 (CHEMBL4104957) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Karos Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of TPH2 (unknown origin) | Bioorg Med Chem Lett 27: 413-419 (2017) Article DOI: 10.1016/j.bmcl.2016.12.053 BindingDB Entry DOI: 10.7270/Q21V5H7S | |||||||||||
More data for this Ligand-Target Pair |