Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tubulin beta chain' and Ligand = 'BDBM50500400'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tubulin beta chain (Sus scrofa)	BDBM50500400 (CHEMBL3747196) Show SMILES COc1ccc(NC(=O)C(=O)c2cn(C(C)C)c3ccccc23)cn1 Show InChI InChI=1S/C19H19N3O3/c1-12(2)22-11-15(14-6-4-5-7-16(14)22)18(23)19(24)21-13-8-9-17(25-3)20-10-13/h4-12H,1-3H3,(H,21,24)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Sheffield Curated by ChEMBL					Assay Description Displacement of [3H]-colchicine from biotinylated porcine tubulin after 2 hrs by competitive binding assay				J Med Chem 58: 9309-33 (2015) Article DOI: 10.1021/acs.jmedchem.5b01312 BindingDB Entry DOI: 10.7270/Q2Z60S2S
					More data for this Ligand-Target Pair
Tubulin beta chain (Sus scrofa)	BDBM50500400 (CHEMBL3747196) Show SMILES COc1ccc(NC(=O)C(=O)c2cn(C(C)C)c3ccccc23)cn1 Show InChI InChI=1S/C19H19N3O3/c1-12(2)22-11-15(14-6-4-5-7-16(14)22)18(23)19(24)21-13-8-9-17(25-3)20-10-13/h4-12H,1-3H3,(H,21,24)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.49E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Sheffield Curated by ChEMBL					Assay Description Inhibition of porcine brain tubulin polymerization assessed as reduction in GTP-induced microtubule assembly after 60 mins by OD340 method				J Med Chem 58: 9309-33 (2015) Article DOI: 10.1021/acs.jmedchem.5b01312 BindingDB Entry DOI: 10.7270/Q2Z60S2S
					More data for this Ligand-Target Pair