Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tubulin beta chain' and Ligand = 'BDBM50500402'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tubulin beta chain (Sus scrofa)	BDBM50500402 (CHEMBL3747607) Show SMILES COCC(C)(C)n1cc(C(=O)C(=O)Nc2ccc(OC)nc2)c2ccccc12 Show InChI InChI=1S/C21H23N3O4/c1-21(2,13-27-3)24-12-16(15-7-5-6-8-17(15)24)19(25)20(26)23-14-9-10-18(28-4)22-11-14/h5-12H,13H2,1-4H3,(H,23,26)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Sheffield Curated by ChEMBL					Assay Description Displacement of [3H]-colchicine from biotinylated porcine tubulin after 2 hrs by competitive binding assay				J Med Chem 58: 9309-33 (2015) Article DOI: 10.1021/acs.jmedchem.5b01312 BindingDB Entry DOI: 10.7270/Q2Z60S2S
					More data for this Ligand-Target Pair
Tubulin beta chain (Sus scrofa)	BDBM50500402 (CHEMBL3747607) Show SMILES COCC(C)(C)n1cc(C(=O)C(=O)Nc2ccc(OC)nc2)c2ccccc12 Show InChI InChI=1S/C21H23N3O4/c1-21(2,13-27-3)24-12-16(15-7-5-6-8-17(15)24)19(25)20(26)23-14-9-10-18(28-4)22-11-14/h5-12H,13H2,1-4H3,(H,23,26)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Sheffield Curated by ChEMBL					Assay Description Inhibition of porcine brain tubulin polymerization assessed as reduction in GTP-induced microtubule assembly after 60 mins by OD340 method				J Med Chem 58: 9309-33 (2015) Article DOI: 10.1021/acs.jmedchem.5b01312 BindingDB Entry DOI: 10.7270/Q2Z60S2S
					More data for this Ligand-Target Pair