Compile Data Set for Download or QSAR

Found 7 hits Enz. Inhib. hit(s) with Target = 'Type-1 angiotensin II receptor' and Ligand = 'BDBM50030719'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Type-1 angiotensin II receptor (RABBIT)	BDBM50030719 (4-[[2'-[N-(tert-Butoxycarbonyl)sulfamoyl]biphenyl-...) Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C34H38F3N5O6S/c1-6-8-13-29-39-42(27-20-24(38-30(43)7-2)18-19-26(27)34(35,36)37)32(45)41(29)21-22-14-16-23(17-15-22)25-11-9-10-12-28(25)49(46,47)40-31(44)48-33(3,4)5/h9-12,14-20H,6-8,13,21H2,1-5H3,(H,38,43)(H,40,44)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.290	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Tested for in vitro binding affinity against angiotensin I (AT1) receptor to competitively block the specific binding of [125I]- [Sar1,Ile8] AII to a...				J Med Chem 37: 4464-78 (1995) BindingDB Entry DOI: 10.7270/Q2WD3ZK5
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50030719 (4-[[2'-[N-(tert-Butoxycarbonyl)sulfamoyl]biphenyl-...) Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C34H38F3N5O6S/c1-6-8-13-29-39-42(27-20-24(38-30(43)7-2)18-19-26(27)34(35,36)37)32(45)41(29)21-22-14-16-23(17-15-22)25-11-9-10-12-28(25)49(46,47)40-31(44)48-33(3,4)5/h9-12,14-20H,6-8,13,21H2,1-5H3,(H,38,43)(H,40,44)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.290	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.				J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50030719 (4-[[2'-[N-(tert-Butoxycarbonyl)sulfamoyl]biphenyl-...) Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C34H38F3N5O6S/c1-6-8-13-29-39-42(27-20-24(38-30(43)7-2)18-19-26(27)34(35,36)37)32(45)41(29)21-22-14-16-23(17-15-22)25-11-9-10-12-28(25)49(46,47)40-31(44)48-33(3,4)5/h9-12,14-20H,6-8,13,21H2,1-5H3,(H,38,43)(H,40,44)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	0.290	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro ability of the compound to inhibit the binding of radioligand 125I[Sar1,IIe8]AII to AT1 receptor from rabbit aorta				Bioorg Med Chem Lett 4: 2787-2792 (1994) Article DOI: 10.1016/S0960-894X(01)80595-3 BindingDB Entry DOI: 10.7270/Q2WS8T68
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50030719 (4-[[2'-[N-(tert-Butoxycarbonyl)sulfamoyl]biphenyl-...) Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C34H38F3N5O6S/c1-6-8-13-29-39-42(27-20-24(38-30(43)7-2)18-19-26(27)34(35,36)37)32(45)41(29)21-22-14-16-23(17-15-22)25-11-9-10-12-28(25)49(46,47)40-31(44)48-33(3,4)5/h9-12,14-20H,6-8,13,21H2,1-5H3,(H,38,43)(H,40,44)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	0.290	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at AT1 receptor in rabbit aorta membranes				Citation and Details Article DOI: 10.1007/s00044-013-0831-x BindingDB Entry DOI: 10.7270/Q2C82BRJ
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50030719 (4-[[2'-[N-(tert-Butoxycarbonyl)sulfamoyl]biphenyl-...) Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C34H38F3N5O6S/c1-6-8-13-29-39-42(27-20-24(38-30(43)7-2)18-19-26(27)34(35,36)37)32(45)41(29)21-22-14-16-23(17-15-22)25-11-9-10-12-28(25)49(46,47)40-31(44)48-33(3,4)5/h9-12,14-20H,6-8,13,21H2,1-5H3,(H,38,43)(H,40,44)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	0.290	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor				Citation and Details Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50030719 (4-[[2'-[N-(tert-Butoxycarbonyl)sulfamoyl]biphenyl-...) Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C34H38F3N5O6S/c1-6-8-13-29-39-42(27-20-24(38-30(43)7-2)18-19-26(27)34(35,36)37)32(45)41(29)21-22-14-16-23(17-15-22)25-11-9-10-12-28(25)49(46,47)40-31(44)48-33(3,4)5/h9-12,14-20H,6-8,13,21H2,1-5H3,(H,38,43)(H,40,44)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	0.290	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor				Citation and Details Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Homo sapiens (Human))	BDBM50030719 (4-[[2'-[N-(tert-Butoxycarbonyl)sulfamoyl]biphenyl-...) Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C34H38F3N5O6S/c1-6-8-13-29-39-42(27-20-24(38-30(43)7-2)18-19-26(27)34(35,36)37)32(45)41(29)21-22-14-16-23(17-15-22)25-11-9-10-12-28(25)49(46,47)40-31(44)48-33(3,4)5/h9-12,14-20H,6-8,13,21H2,1-5H3,(H,38,43)(H,40,44)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against angiotensin II receptor type 1, in human adrenal membrane preparations.				J Med Chem 38: 3741-58 (1995) BindingDB Entry DOI: 10.7270/Q2Q81C35
					More data for this Ligand-Target Pair