Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Type-1 angiotensin II receptor' and Ligand = 'BDBM50283763'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Type-1 angiotensin II receptor (RABBIT)	BDBM50283763 (CHEMBL321531 | N-(3-{3-Butyl-4-[2'-(2-chloro-benzo...) Show SMILES CCCCc1nn(-c2cc(NC(C)=O)ccc2Cl)c(=O)n1Cc1ccc(cc1F)-c1cc(CCC)ccc1S(=O)(=O)NC(=O)c1ccccc1Cl Show InChI InChI=1S/C37H36Cl2FN5O5S/c1-4-6-12-35-42-45(33-21-27(41-23(3)46)16-17-31(33)39)37(48)44(35)22-26-15-14-25(20-32(26)40)29-19-24(9-5-2)13-18-34(29)51(49,50)43-36(47)28-10-7-8-11-30(28)38/h7-8,10-11,13-21H,4-6,9,12,22H2,1-3H3,(H,41,46)(H,43,47)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro ability of the compound to inhibit the binding of radioligand 125I[Sar1,IIe8]AII to AT1 receptor from rabbit aorta				Bioorg Med Chem Lett 4: 2787-2792 (1994) Article DOI: 10.1016/S0960-894X(01)80595-3 BindingDB Entry DOI: 10.7270/Q2WS8T68
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Homo sapiens (Human))	BDBM50283763 (CHEMBL321531 | N-(3-{3-Butyl-4-[2'-(2-chloro-benzo...) Show SMILES CCCCc1nn(-c2cc(NC(C)=O)ccc2Cl)c(=O)n1Cc1ccc(cc1F)-c1cc(CCC)ccc1S(=O)(=O)NC(=O)c1ccccc1Cl Show InChI InChI=1S/C37H36Cl2FN5O5S/c1-4-6-12-35-42-45(33-21-27(41-23(3)46)16-17-31(33)39)37(48)44(35)22-26-15-14-25(20-32(26)40)29-19-24(9-5-2)13-18-34(29)51(49,50)43-36(47)28-10-7-8-11-30(28)38/h7-8,10-11,13-21H,4-6,9,12,22H2,1-3H3,(H,41,46)(H,43,47)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory concentration of the compound against AT1 receptor from human adrenal tissues.				Bioorg Med Chem Lett 4: 2787-2792 (1994) Article DOI: 10.1016/S0960-894X(01)80595-3 BindingDB Entry DOI: 10.7270/Q2WS8T68
					More data for this Ligand-Target Pair