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Found 1 hit Enz. Inhib. hit(s) with Target = 'Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor' and Ligand = 'BDBM50469901'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Type-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor


(RAT)		BDBM50469901
PNG
(GR-138950 | SAPRISARTAN)
Show SMILES CCc1nc(C2CC2)c(C(N)=O)n1Cc1ccc2oc(c(Br)c2c1)-c1ccccc1NS(=O)(=O)C(F)(F)F
Show InChI InChI=1S/C25H22BrF3N4O4S/c1-2-19-31-21(14-8-9-14)22(24(30)34)33(19)12-13-7-10-18-16(11-13)20(26)23(37-18)15-5-3-4-6-17(15)32-38(35,36)25(27,28)29/h3-7,10-11,14,32H,2,8-9,12H2,1H3,(H2,30,34)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
 0.501n/an/an/an/an/an/an/an/a



Glaxo Research and Development Ltd.

Curated by ChEMBL


Assay Description
Tested for in vitro binding affinity against angiotensin II receptor of rat liver

J Med Chem 37: 3108-20 (1994)


Article DOI: 10.1021/jm00045a016
BindingDB Entry DOI: 10.7270/Q21R6T7V
More data for this
Ligand-Target Pair