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Found 1 hit Enz. Inhib. hit(s) with Target = 'Type-2 angiotensin II receptor' and Ligand = 'BDBM50043458'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Type-2 angiotensin II receptor


(RAT)		BDBM50043458
PNG
((2-Chloro-phenyl)-{ethyl-[4-(2-ethyl-5,7-dimethyl-...)
Show SMILES CCN(C(C(O)=O)c1ccccc1Cl)c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1
Show InChI InChI=1S/C27H29ClN4O2/c1-5-23-30-24-17(3)15-18(4)29-26(24)32(23)16-19-11-13-20(14-12-19)31(6-2)25(27(33)34)21-9-7-8-10-22(21)28/h7-15,25H,5-6,16H2,1-4H3,(H,33,34)
PDB

KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a>1.10E+5n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro antagonist activity against angiotensin II type 2 (AT2) receptor in rat midbrain using [125I]- Sar, Ile AII.

J Med Chem 36: 4239-49 (1994)


BindingDB Entry DOI: 10.7270/Q22V2F6P
More data for this
Ligand-Target Pair