BindingDB PrimarySearch

Found 10 hits Enz. Inhib. hit(s) with Target = 'Type-2 angiotensin II receptor' and Ligand = 'BDBM50156173'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50156173 ((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Sherbrooke Curated by ChEMBL					Assay Description Binding affinity to AT2 receptor (unknown origin)				ACS Med Chem Lett 5: 1129-32 (2014) Article DOI: 10.1021/ml500278g BindingDB Entry DOI: 10.7270/Q2BV7J7R
Universit£ de Sherbrooke Curated by ChEMBL					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50156173 ((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity to type-2 angiotensin-2 receptor (unknown origin)				Bioorg Med Chem Lett 26: 1355-9 (2016) Article DOI: 10.1016/j.bmcl.2015.10.084 BindingDB Entry DOI: 10.7270/Q2SN0BT6
Uppsala University Curated by ChEMBL					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50156173 ((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]-Ang II from pig uterus membrane angiotensin II type 2 (AT2) receptor				J Med Chem 47: 5995-6008 (2004) Article DOI: 10.1021/jm049715t BindingDB Entry DOI: 10.7270/Q29Z95PH
Uppsala University Curated by ChEMBL					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Sus scrofa)	BDBM50156173 ((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity to pig AT2 receptor				Bioorg Med Chem Lett 24: 476-9 (2014) Article DOI: 10.1016/j.bmcl.2013.12.040 BindingDB Entry DOI: 10.7270/Q2B859KQ
Uppsala University Curated by ChEMBL					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50156173 ((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity to AT2 receptor				Bioorg Med Chem 18: 4570-90 (2010) Article DOI: 10.1016/j.bmc.2010.03.064 BindingDB Entry DOI: 10.7270/Q2VD70F0
Uppsala University Curated by ChEMBL					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Sus scrofa)	BDBM50156173 ((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116790 BindingDB Entry DOI: 10.7270/Q2ZW1QXF
TBA					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Sus scrofa)	BDBM50156173 ((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]angiotensin 2 from AT2 receptor in pig uterus membrane after 1.5 hrs by gamma counting				Bioorg Med Chem 18: 4570-90 (2010) Article DOI: 10.1016/j.bmc.2010.03.064 BindingDB Entry DOI: 10.7270/Q2VD70F0
Uppsala University Curated by ChEMBL					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50156173 ((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL) Curated by ChEMBL					Assay Description Binding affinity to AT2 receptor (unknown origin)				J Med Chem 61: 9811-9840 (2018) Article DOI: 10.1021/acs.jmedchem.8b00294 BindingDB Entry DOI: 10.7270/Q2XK8J7N
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50156173 ((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116790 BindingDB Entry DOI: 10.7270/Q2ZW1QXF
TBA					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50156173 ((1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116804 BindingDB Entry DOI: 10.7270/Q2WH2V1D
TBA					More data for this Ligand-Target Pair